Category: Productivity

Improving Productivity

Is There Hope for Improving Drug Development Productivity?

I was recently reading yet another paper bemoaning the dropping productivity in drug development. The authors were discussing the most likely explanations for the decline, which were

  • tighter regulation
  • illusory decline (no actual decline)
  • depletion of low-hanging fruit
  • increasing risk aversion by the drug companies
  • rising hurdles on safety

I mention this only because the paper was written in 1978 Continue reading “Improving Productivity”

Decision Making

One mystery of drug productivity at large pharma is the persistent low productivity despite the fact that there are tremendously talented scientists at every large pharma company. Their expertise is often encyclopedic, and their creativity is often very evident. Despite this, productivity at large companies have been less than impressive. The productivity appears to be low in comparison to small biotechs, but even more shocking, Continue reading “Decision Making”